Product Information and Use

Q: How does Rx Destroyer™ pharmaceutical disposal system work?

Rx Destroyer™ patented* formula begins dissolving medications on contact. As medications are dispersed in the activated carbon slurry, diversion is discouraged and potential environmental harm is reduced. Product is “ready-to-use”…No adding water needed. Simply add medications…when full discard into common trash, and always follow applicable federal, state, local, and tribal laws/regulations.
Additional information and test reports.

Q: What items may NOT be put in the Rx Destroyer™ pharmaceutical disposal system?

  • DO NOT add effervescent or antacid or gassing medications.
  • DO NOT add hardware such as syringes, glass or bottles. Dispose of physical vials and syringes into red sharp containers.
  • DO NOT place Hazardous Materials (HAZMAT) or any hazardous pharmaceuticals in container unless user has determined they can safely incinerate or dispose according to rules & laws under which they are governed. For more information on hazardous materials please review following links:
  • DO NOT add Leaf Marijuana
  • DO NOT add Medications Insoluble in H2O or Oil Based Medications
  • PurduePharm’s version of Oxycontin is “Non-Divertible”, unique gel formulation may not dissolve timely in Rx Destroyer™. Oxycontin or variations made by Purdue may be candidate for RCRA waste – consult internal Pharmacist.


A) To date, Rx Destroyer™ pharmacist has reviewed the following “Non-Divertible” drugs and have been deemed them acceptable in Rx Destroyer™:
Naltrexone | Opana | Suboxone
B) “Water Solubility” is the key for adsorption. Medications have varying levels of water solubility thus have differing neutralization times yet fall within an expected 7 day period.
C) Generator is ultimately responsible for additives to product. If ever in doubt what can be added to Rx Destroyer™, always follow applicable federal, state, local, and tribal laws/regulations. Contact Rx Destroyer™ customer service directly or submit email inquiries to

Q: How is Rx Destroyer™ superior to “dry” medication disposal products on market?

“Product is “Ready-to-Use”… No Water… No Batteries”

  • Rx Destroyer™ patented* ready-to-use formula contains 2 major components; chemically engineered fast dissolving liquid and specially tuned activated carbon. Products containing “dry” activated formula are opportunity for diversion and abuse because the adsorption (transfer) process cannot occur until pills are dissolved.
  • Seeing is believing. Look inside the “dry” product containers and see pills sitting on top of carbon in their original form. These conditions are prime for diversion or abuse and would be considered by the industry as “stock piling“. This method does not meet DEA definition of non-retrievable.
  • “Dry” activated carbon is considered a fire hazard and may not be allowed at healthcare facilities with or without an SDS Sheet. Rx Destroyer™ aquas solutions are not a fire hazard – Rx Destroyers™ SDS (safety Data Sheet).

Rx Destroyer™ formulated products begin working on contact. As medications are dispersed in the activated carbon slurry, diversion is discouraged and potential environmental harm is reduced. Follow link for test reports.


Q: What is the shelf life of Rx Destroyer™

Rx Destroyer™ products are manufactured on-demand and processed based upon common FIFO (First-In,  First-Out) inventory methods. Subsequently, orders shipped have a “Born On” date no later than 30 days prior to ship date.

  • Unopened containers – (5) years.
  • Once medications have been added, no longer than (1) year is suggested. If additives are bio based, user may want to dispose as soon as possible to avoid odors and or potential mold growth. As it is impossible to predict all additive combinations, please consult and follow facilities, local, state, tribal and or federal guidelines.

Q: Can Rx Destroyer™ pharmaceutical disposal system accommodate transdermal patches?

Yes. Simply remove from packaging and drop into Rx Destroyer™ pharmaceutical disposal system. If patch is large, Rx Destroyer™ suggests folding with patch’s skin surface facing outward. As always, following safety guidelines, rules and regulations by which you are governed.

*Note: Ultimately, it is the prerogative and responsibility of the Rx Destroyer™ User to add and manage drugs at their discretion. Subsequently, User must follow rules and regulations under which they are governed for safe and responsible disposal.

Q: Can I use Rx Destroyer™ pharmaceutical disposal system more than once?

Rx Destroyer™ pharmaceutical disposal system is a multiple use system. Continue to add until reaching 2″ of the bottle opening. When not in use, always store in a controlled, safe and secure location.

Q: What do I do when the container is full?

Rx Destroyer™ was developed to be disposed in common trash. Some business types require incineration to mitigate risk. If you need to explore incineration , please call for affordable pickup or mail-back options in your part of country.

Always review your company’s processes and policies or consult local, state, tribal or federal agencies for regulations that apply to your facilities prior to use.

Q: Is there an easier method to mass load medications into the Rx Destroyer™

Rx Destroyer™ accessories includes our standard funnel RXFUN and RXFUN32 deluxe model which physically attached to containers. Both allow for easy and convenient dispensing of mass quantities.

Q: I see capsules floating in Rx Destroyer™. Have these medications been neutralized?

Capsule and contents may be lighter than water which is why you may see some floating. Capsule shells come in hard or soft shells manufactured in variety of materials such as protein based gelatin and other bio-safe polymers. During the adsorption/destruction/neutralization process some may appear in the original form or varying levels of collapse. These shell conditions are considered normal and expected.

Example: OROS (Osmotic Release Oral System) is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through the opening in the tablet. OROS is a trademarked name owned by ALZA Corporation, which pioneered the use of osmotic pumps for oral drug delivery.

Like the human stomach, Rx Destroyer™ formulation has penetrated capsule and neutralization has begun or complete. Many variables determine if capsule shell completely dissolves or remains intact. In fact, like floating capsule shells in the Rx destroyer™, it’s common for end-users to find capsule shells in stool.

Q: How long does it take to adsorb or deem drugs irretrievable?

Adsorption or irratrievability time varies depending on many factors including environment, drug type, quantity and cocktail combinations. For this reason, we recommend keeping Rx Destroyer™ containers in-use kept in in a controlled and secure location.

Q: How can our facility determine which medications are considered hazardous?

Due to shear number of medication variations including new product introductions, there is no single source answer. In fact, the federal government has not updated the U-List and P-List since 1975. To make matters more challenging, each facility is responsible for identifying hazardous waste.

Under the RCRA, a solid waste is hazardous waste if it exhibits one of four characteristics—ignitability, corrosivity, toxicity, or reactivity—or if it is specifically named on one of the four EPA lists of hazardous waste, P, U, F, and K, in 40 CFR §261.2, subpart D. Drugs listed under P and U include specific unused chemicals; drugs under U are toxic, while those under P are considered acutely toxic.

Rx Destroyer™ recommends a combination of efforts including staff and consulting pharmacist review site formulary. If additional assistance is required, there are a number of outside analysis firms available to perform waste analysis. Also, be aware local, state and tribal regulations may vary as to which drugs and what quantity qualify them as hazardous.

Q: Can alcohol such as isopropyl alcohol be used in Rx Destroyer™?

Alcohol is considered flammable and subsequently considered hazardous. Hazardous items are not to be placed in Rx Destroyer™.

Q: Why and when are the Rx Destroyer™ Hardener Pouch(s) added to the Liquids bottle?

Rx Destroyer™ Hardener helps prevent potential messy liquid spills in the waste stream. DUST FREE formulation converts Rx Liquids™ to Solid Gel meeting SW-846 Test Method (paint filter liquids test). Simply add pouch to container… No cutting or pouring. No Powder Plumes. No Mess. Pouch wrapper developed to begin dissolving on contact.

  • (1) Hardener Pouch per 64oz “container”
    • Ex.1: (1) Hardener pouch per 64oz container
    • Ex.2:  (2) Hardener pouches per “1 Gallon” container
  • Prior to discarding, tightly replace the cap and gently shake bottle until the fluid becomes a non-movable solid gel

Q: Can Hardener Pouches Be Used with All-Purpose Formulations?

Yes. However, the hardener is optional.

LIQUIDS products includes enough hardener pouches for each bottle.

Additional Pouches may be ordered separately.

Product performs exceptionally well on container contents containing at least 10% water.

Some medications, drugs or combinations may not be compatible with Rx Hardener™  due to their chemical composition.


Q: Where can I purchase Rx Destroyer™ pharmaceutical disposal system?

  1. Order Direct:  24/7 online or call (888) 608-5160 M-F 8am-4pm Central Time
  2. Order from Authorized Distributor:  see bottom of home page for partial list
  3. Order Single Bottles: “Google” Buy Rx Destroyer™ look for “Authorized” Rx Destroyer™ distributors
  4. Now available at all Walgreen’s across the USA

Important Documentation

Q: Why do I need a Witness Destruction Log?

All controlled substance destruction must be recorded on a Witness Destruction Log (see log example). This means that two witnesses have overseen the on-site destruction of the controlled substances. The log records date, dosage, amount destroyed, destruction method and date with signature of each witness. The witness log is kept on-site for 3 to 5 years per state regulations. Since Rx Destroyer™ is used to waste non-hazardous controlled substances, the witness log could be reviewed to ensure that only non-hazardous drugs were placed into the Rx Destroyer™ bottle. The witness log verifies that the Rx Destroyer™ contains a non-hazardous carbon mixture and therefore the bottles can be discarded into a non-RCRA pharmaceutical waste bin or non-hazardous industrial waste bin.

Compliance Laws & Regulations

Q: What’s the DEA’s definition of disposal of pharmaceutical wastage?

Excerpt per DEA regulations (e.g., § 1304.22(c) Final Rule – “controlled substance dispensed for immediate administration pursuant to an order for medication in an institutional setting remains under the custody and control of that registered institution even if the substance is not fully exhausted (e.g., some of the substance remains in a vial, tube, transdermal patch, or syringe after administration but cannot or may not be further utilized, commonly referred to as ‘drug wastage’ and ‘pharmaceutical wastage’). Such remaining substance must be properly recorded, stored, and destroyed in accordance with DEA regulations (e.g., § 1304.22(c)), and all applicable Federal, State, tribal, and local laws and regulations, although the destruction need not be recorded on a DEA Form 41.” Click here for complete 21 CFR 1300, 1301 and 1304 Disposal of Controlled Substances; Final Rule.
Should you have any questions pertaining to this matter, please contact your local DEA field office, or you may contact the DEA Office of Diversion Control, Liaison and Policy Section, at (202) 307-7297.

Q: What’s the DEA definition on non-retrievable?

The final rule implements a standard of destruction: non-retrievable. The process utilized to render a substance “non-retrievable” shall permanently alter the substance’s physical or chemical condition or state through irreversible means and thereby render the substance unavailable and unusable for all practical purposes. A substance is considered “non-retrievable” when it cannot be transformed to a physical or chemical condition or state as a controlled substance or controlled substance analogue.

Q: Does activated carbon render substances non-retrievable?

Activated carbon is a form of chemical destruction. Chemical destruction is recognized in DEA regulations. Rx Destroyer™ uses activated carbon.

DEA DEFINITION: “Non-Retrievable”

Q: What is RCRA?

The Resource Conservation and Recovery Act (RCRA) gives EPA the authority to control hazardous waste from the “cradle-to-grave.” This includes the generation, transportation, treatment, storage, and disposal of hazardous waste. RCRA also set forth a framework for the management of non-hazardous solid wastes. The 1986 amendments to RCRA enabled EPA to address environmental problems that could result from underground tanks storing petroleum and other hazardous substances.

With regard to pharmaceutical waste disposal and other regulated activities associated with pharmaceuticals, always follow applicable federal, state, local, and tribal laws/regulations. If your facility requires and does not have a pharmaceutical waste service provider, Rx Destroyer™ can recommend a service provider.

Q: Does Rx Destroyer™ meet California’s Safe Drinking Water and Toxic Enforcement Act of 1986 (“Prop 65”)?

Rx Destroyer™ products do not contain items in the Prop 65 chemical list. Therefore, Rx Destroyer™ products do not require the label notification as directed in the rule.
Additional Information & Act Specifics:

Q: Does Rx Destroyer™ comply with Hazardous Waste standards such as USP 800 & 40 CFR Parts 261, 262, 264, 265, 266, 268, 270,and 273?

Rx Destroyer™ products DO NOT allow hazardous waste and do not apply to these standards. If product user determines it can safely manage hazardous medical waste, then it is the users prerogative and complete sole responsibility to manage according to the rules and regulations under which they’re governed.

Link to: USP 800
Link to: 40 CFR Parts 261, 262, 264, 265, 266, 268, 270,and 273?

Q: What US Patents* apply to Rx Destroyer™.

  • US Patent #9,403,197 Issued August 2nd, 2016 applies to Rx DestroyerTM used with the hardener pouches

Q: What information does a Waste Hauler need to accept Rx Destroyer™ products.

Within the acute healthcare market, major waste hauler policies state they will accept regulated medical waste when it’s been properly documented and segregated. Rx Destroyer™ products are typically considered Non-RCRA Pharmaceuticals and Non-Hazardous Waste must be characterized and certified as non-RCRA hazardous material by the generator. In cases where a facility has determined they can safely commingle hazardous and non-hazardous in Rx Destroyer™, Generator shall follow worse case disposal scenario processes to ensure safe and proper disposal of bottle contents. The “Witness Disposal Log” is the Generator’s record and proof of Rx Destroyer™ contents.


DO NOT OPEN. Consult supervisor immediately. Take all necessary steps to safely transfer bottle(s) to controlled disposal area. Review list of additives to ensure gas causing items or combinations of gas causing items are not replicated.

Generators are ultimately responsible for product contents, if hazardous medications are loaded into the Rx Destroyer™, then the bottle must be disposed as RCRA hazardous waste. Consult supervisor for facilities, local, state or federal rules/ guidelines.

  • Rx Destroyer TM contents are Eco-Friendly and in itself non-toxic or hazardous. See SDS now.
  • Follow facility, local, state and federal guidelines for cleanup. Always maintain a list of medications added to system.
  • If in doubt, contact Poison Control Center (800) 222-1222


  • Simply allow to thaw and use as directed.
  • If container appears to be damaged in anyway discard.